Mistral: Mixtral 8x22B Instruct vs OpenAI: GPT Audio

Neither wins outright: Mistral: Mixtral 8x22B Instruct is the pick when cost matters at scale, OpenAI: GPT Audio when you need to fit long inputs in one request.

Key numbers

SpecMistral: Mixtral 8x22B InstructOpenAI: GPT Audio
ProviderMistral AIOpenAI
Input price (per 1M tokens)$2.00$2.50
Output price (per 1M tokens)$6.00$10.00
Blended price (3:1 input/output)$3.00$4.38
Cheaper than … of all models we track20%13%
Context window66K tokens (~98 pages)128K tokens (~192 pages)
Larger context than … of all models11%14%
Max output per response52K tokens (~39,300 words)16K tokens (~12,300 words)
Input typestext, filetext, audio
Output typestexttext, audio
Free variantNoNo
Listed since2024-04-172026-01-19
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What it costs for real workloads

Monthly cost at list price for five common workloads. Token counts per unit are stated so you can scale them to your own traffic. A workload that does not fit a model's context window is marked rather than priced.

Workload (per month)Mistral: Mixtral 8x22B InstructOpenAI: GPT AudioDifference
Customer-support chatbot
50,000 conversations — each a 6-turn conversation (1,500 in / 400 out tokens)
$270$388Mistral: Mixtral 8x22B Instruct saves $118
RAG search over documents
20,000 questions — each a question answered from ~8 retrieved passages (6,000 in / 500 out tokens)
$300$400Mistral: Mixtral 8x22B Instruct saves $100
Coding / tool-using agent
2,000 tasks — each a multi-step task with tool calls and file context (60,000 in / 6,000 out tokens)
Doesn't fit context$420—
Batch summarisation
10,000 documents — each a 6,000-word report summarised to a page (8,000 in / 600 out tokens)
$196$260Mistral: Mixtral 8x22B Instruct saves $64.00
Long-document analysis
500 documents — each a 150-page contract or codebase read in one pass (100,000 in / 2,000 out tokens)
Doesn't fit context$135—

Capabilities side by side

CapabilityMistral: Mixtral 8x22B InstructOpenAI: GPT AudioWhat it lets you do
Tool / function calling✓ Yes✓ Yescall your APIs and run agent loops
Structured output (JSON schema)✓ Yes✓ Yesreturn JSON that validates against your schema
Reasoning / thinking mode——spend extra tokens thinking before answering hard problems
Image input——read screenshots, charts and scanned pages
Audio input—✓ Yestake speech or audio directly
File / PDF input✓ Yes—accept documents without your own parsing step
Image output——generate images, not just text
Built-in web search——answer from live web results
Seed (reproducible sampling)✓ Yes✓ Yesrepeat a generation for tests and evals
Log-probabilities—✓ Yesread token confidence for classification and scoring

From each model's published parameters and input/output types. “—” means not advertised, not proven absent.

Price history

Which should you choose?

Choose Mistral: Mixtral 8x22B Instruct if…

  • cost matters at scale — it is 31% cheaper on a typical 3:1 input/output mix ($270 vs $388 a month for 50,000 support chats)
  • you need file / PDF input — to accept documents without your own parsing step; OpenAI: GPT Audio does not advertise it
  • you generate long outputs in one go — up to 52K tokens (about 39,300 words) per response

Choose OpenAI: GPT Audio if…

  • you need to fit long inputs in one request — 128K tokens is roughly 192 pages, against 98
  • you need audio input — to take speech or audio directly; Mistral: Mixtral 8x22B Instruct does not advertise it
  • you need log-probabilities — to read token confidence for classification and scoring; Mistral: Mixtral 8x22B Instruct does not advertise it
  • you want the newer model — released 2026-01-19, 21 months after the other

Frequently asked questions

Is Mistral: Mixtral 8x22B Instruct better than OpenAI: GPT Audio?

Neither wins outright: Mistral: Mixtral 8x22B Instruct is the pick when cost matters at scale, OpenAI: GPT Audio when you need to fit long inputs in one request. In short: Mistral: Mixtral 8x22B Instruct when cost matters at scale, you need file / PDF input, you generate long outputs in one go; OpenAI: GPT Audio when you need to fit long inputs in one request, you need audio input, you need log-probabilities, you want the newer model.

Which is cheaper, Mistral: Mixtral 8x22B Instruct or OpenAI: GPT Audio?

Mistral: Mixtral 8x22B Instruct is cheaper: $3.00 vs $4.38 per 1M tokens at a typical 3:1 input/output mix, 31% less. For 50,000 support conversations a month that is $270 against $388.

How much do Mistral: Mixtral 8x22B Instruct and OpenAI: GPT Audio cost per million tokens?

Mistral: Mixtral 8x22B Instruct costs $2.00 per 1M input tokens and $6.00 per 1M output tokens; OpenAI: GPT Audio costs $2.50 input and $10.00 output. Output tokens are billed separately, so long answers shift the gap.

Which has the bigger context window, Mistral: Mixtral 8x22B Instruct or OpenAI: GPT Audio?

OpenAI: GPT Audio: 128K tokens, about 192 pages, against 66K (about 98 pages) for Mistral: Mixtral 8x22B Instruct.

Do Mistral: Mixtral 8x22B Instruct and OpenAI: GPT Audio support function calling and JSON output?

Tool calling — Mistral: Mixtral 8x22B Instruct: yes, OpenAI: GPT Audio: yes. JSON-schema structured output — Mistral: Mixtral 8x22B Instruct: yes, OpenAI: GPT Audio: yes.

Can Mistral: Mixtral 8x22B Instruct or OpenAI: GPT Audio read images?

Neither accepts image input — both are text-in models.

Is Mistral: Mixtral 8x22B Instruct or OpenAI: GPT Audio free to use?

No free variant is listed for either; both are pay-per-token.

What is the maximum output length of Mistral: Mixtral 8x22B Instruct and OpenAI: GPT Audio?

Mistral: Mixtral 8x22B Instruct can write up to 52K tokens (about 39,300 words) per response; OpenAI: GPT Audio up to 16K (about 12,300 words).

When were Mistral: Mixtral 8x22B Instruct and OpenAI: GPT Audio released?

Mistral: Mixtral 8x22B Instruct was listed on 2024-04-17; OpenAI: GPT Audio on 2026-01-19.

About the two models

OpenAI

OpenAI: GPT Audio

The gpt-audio model is OpenAI's first generally available audio model. The new snapshot features an upgraded decoder for more natural sounding voices and maintains better voice consistency. Audio is priced...

Full OpenAI: GPT Audio specs →

Compare Mistral: Mixtral 8x22B Instruct with other models

Compare OpenAI: GPT Audio with other models

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