Mistral: Mixtral 8x22B Instruct vs OpenAI: GPT-4o

Neither wins outright: Mistral: Mixtral 8x22B Instruct is the pick when cost matters at scale, OpenAI: GPT-4o when you need to fit long inputs in one request.

Key numbers

SpecMistral: Mixtral 8x22B InstructOpenAI: GPT-4o
ProviderMistral AIOpenAI
Input price (per 1M tokens)$2.00$2.50
Output price (per 1M tokens)$6.00$10.00
Blended price (3:1 input/output)$3.00$4.38
Cheaper than … of all models we track20%13%
Context window66K tokens (~98 pages)128K tokens (~192 pages)
Larger context than … of all models11%14%
Max output per response52K tokens (~39,300 words)16K tokens (~12,300 words)
Input typestext, filetext, image, file
Output typestexttext
Free variantNoNo
Listed since2024-04-172024-05-13
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What it costs for real workloads

Monthly cost at list price for five common workloads. Token counts per unit are stated so you can scale them to your own traffic. A workload that does not fit a model's context window is marked rather than priced.

Workload (per month)Mistral: Mixtral 8x22B InstructOpenAI: GPT-4oDifference
Customer-support chatbot
50,000 conversations — each a 6-turn conversation (1,500 in / 400 out tokens)
$270$388Mistral: Mixtral 8x22B Instruct saves $118
RAG search over documents
20,000 questions — each a question answered from ~8 retrieved passages (6,000 in / 500 out tokens)
$300$400Mistral: Mixtral 8x22B Instruct saves $100
Coding / tool-using agent
2,000 tasks — each a multi-step task with tool calls and file context (60,000 in / 6,000 out tokens)
Doesn't fit context$420—
Batch summarisation
10,000 documents — each a 6,000-word report summarised to a page (8,000 in / 600 out tokens)
$196$260Mistral: Mixtral 8x22B Instruct saves $64.00
Long-document analysis
500 documents — each a 150-page contract or codebase read in one pass (100,000 in / 2,000 out tokens)
Doesn't fit context$135—

Capabilities side by side

CapabilityMistral: Mixtral 8x22B InstructOpenAI: GPT-4oWhat it lets you do
Tool / function calling✓ Yes✓ Yescall your APIs and run agent loops
Structured output (JSON schema)✓ Yes✓ Yesreturn JSON that validates against your schema
Reasoning / thinking mode——spend extra tokens thinking before answering hard problems
Image input—✓ Yesread screenshots, charts and scanned pages
Audio input——take speech or audio directly
File / PDF input✓ Yes✓ Yesaccept documents without your own parsing step
Image output——generate images, not just text
Built-in web search—✓ Yesanswer from live web results
Seed (reproducible sampling)✓ Yes✓ Yesrepeat a generation for tests and evals
Log-probabilities—✓ Yesread token confidence for classification and scoring

From each model's published parameters and input/output types. “—” means not advertised, not proven absent.

Price history

Which should you choose?

Choose Mistral: Mixtral 8x22B Instruct if…

  • cost matters at scale — it is 31% cheaper on a typical 3:1 input/output mix ($270 vs $388 a month for 50,000 support chats)
  • you generate long outputs in one go — up to 52K tokens (about 39,300 words) per response

Choose OpenAI: GPT-4o if…

  • you need to fit long inputs in one request — 128K tokens is roughly 192 pages, against 98
  • you need image input — to read screenshots, charts and scanned pages; Mistral: Mixtral 8x22B Instruct does not advertise it
  • you need built-in web search — to answer from live web results; Mistral: Mixtral 8x22B Instruct does not advertise it
  • you need log-probabilities — to read token confidence for classification and scoring; Mistral: Mixtral 8x22B Instruct does not advertise it

Frequently asked questions

Is Mistral: Mixtral 8x22B Instruct better than OpenAI: GPT-4o?

Neither wins outright: Mistral: Mixtral 8x22B Instruct is the pick when cost matters at scale, OpenAI: GPT-4o when you need to fit long inputs in one request. In short: Mistral: Mixtral 8x22B Instruct when cost matters at scale, you generate long outputs in one go; OpenAI: GPT-4o when you need to fit long inputs in one request, you need image input, you need built-in web search, you need log-probabilities.

Which is cheaper, Mistral: Mixtral 8x22B Instruct or OpenAI: GPT-4o?

Mistral: Mixtral 8x22B Instruct is cheaper: $3.00 vs $4.38 per 1M tokens at a typical 3:1 input/output mix, 31% less. For 50,000 support conversations a month that is $270 against $388.

How much do Mistral: Mixtral 8x22B Instruct and OpenAI: GPT-4o cost per million tokens?

Mistral: Mixtral 8x22B Instruct costs $2.00 per 1M input tokens and $6.00 per 1M output tokens; OpenAI: GPT-4o costs $2.50 input and $10.00 output. Output tokens are billed separately, so long answers shift the gap.

Which has the bigger context window, Mistral: Mixtral 8x22B Instruct or OpenAI: GPT-4o?

OpenAI: GPT-4o: 128K tokens, about 192 pages, against 66K (about 98 pages) for Mistral: Mixtral 8x22B Instruct.

Do Mistral: Mixtral 8x22B Instruct and OpenAI: GPT-4o support function calling and JSON output?

Tool calling — Mistral: Mixtral 8x22B Instruct: yes, OpenAI: GPT-4o: yes. JSON-schema structured output — Mistral: Mixtral 8x22B Instruct: yes, OpenAI: GPT-4o: yes.

Can Mistral: Mixtral 8x22B Instruct or OpenAI: GPT-4o read images?

Only OpenAI: GPT-4o accepts image input; Mistral: Mixtral 8x22B Instruct is text-only for input.

Is Mistral: Mixtral 8x22B Instruct or OpenAI: GPT-4o free to use?

No free variant is listed for either; both are pay-per-token.

What is the maximum output length of Mistral: Mixtral 8x22B Instruct and OpenAI: GPT-4o?

Mistral: Mixtral 8x22B Instruct can write up to 52K tokens (about 39,300 words) per response; OpenAI: GPT-4o up to 16K (about 12,300 words).

When were Mistral: Mixtral 8x22B Instruct and OpenAI: GPT-4o released?

Mistral: Mixtral 8x22B Instruct was listed on 2024-04-17; OpenAI: GPT-4o on 2024-05-13.

About the two models

OpenAI

OpenAI: GPT-4o

GPT-4o ("o" for "omni") is OpenAI's latest AI model, supporting both text and image inputs with text outputs. It maintains the intelligence level of [GPT-4 Turbo](/models/openai/gpt-4-turbo) while being twice as...

Full OpenAI: GPT-4o specs →

Compare Mistral: Mixtral 8x22B Instruct with other models

Compare OpenAI: GPT-4o with other models

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