Skills by risk · page 387

Highest-trust agent skills

9,826 skills rated SAFE with grade A or B, best score first. All are grade B today: grade A needs a sandboxed run we do not do for skills yet. Ties are broken by stars, so a repository with many skills can fill a page.

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ModelsAtlas. “Highest-trust agent skills”. Retrieved 30 Oct 2026. https://modelsatlas.com/skills/trusted/page/387
9,826 SAFE skills · page 387 of 410 · ranked by trust score, then stars
Clinical Decision Support✓SAFE B

jimmc414/Kosmos

Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation…

★ 595GitHub stars
Clinical Reports✓SAFE B

jimmc414/Kosmos

Write comprehensive clinical reports including case reports (CARE guidelines), diagnostic reports (radiology/pathology/lab), clinical trial reports (ICH-E3, SAE, CSR), and patient documentation (SOAP, H&P, discharge…

★ 595GitHub stars
Clinvar Database✓SAFE B

jimmc414/Kosmos

Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.

★ 595GitHub starsData & analysis
Cobrapy✓SAFE B

jimmc414/Kosmos

Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.

★ 595GitHub stars
Datacommons Client✓SAFE B

jimmc414/Kosmos

Work with Data Commons, a platform providing programmatic access to public statistical data from global sources. Use this skill when working with demographic data, economic indicators, health statistics, environmental…

★ 595GitHub stars
Denario✓SAFE B

jimmc414/Kosmos

Multiagent AI system for scientific research assistance that automates research workflows from data analysis to publication. This skill should be used when generating research ideas from datasets, developing research…

★ 595GitHub stars
Docx✓SAFE B

jimmc414/Kosmos

Document toolkit (.docx). Create/edit documents, tracked changes, comments, formatting preservation, text extraction, for professional document processing.

★ 595GitHub stars
Ena Database✓SAFE B

jimmc414/Kosmos

Access European Nucleotide Archive via API/FTP. Retrieve DNA/RNA sequences, raw reads (FASTQ), genome assemblies by accession, for genomics and bioinformatics pipelines. Supports multiple formats.

★ 595GitHub starsData & analysis
Esm✓SAFE B

jimmc414/Kosmos

Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this…

★ 595GitHub stars
Exploratory Data Analysis✓SAFE B

jimmc414/Kosmos

Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and…

★ 595GitHub starsData & analysis
Fda Database✓SAFE B

jimmc414/Kosmos

Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.

★ 595GitHub starsData & analysis
Get Available Resources✓SAFE B

jimmc414/Kosmos

This skill should be used at the start of any computationally intensive scientific task to detect and report available system resources (CPU cores, GPUs, memory, disk space). It creates a JSON file with resource…

★ 595GitHub stars
Gtars✓SAFE B

jimmc414/Kosmos

High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis…

★ 595GitHub stars
Histolab✓SAFE B

jimmc414/Kosmos

Digital pathology image processing toolkit for whole slide images (WSI). Use this skill when working with histopathology slides, processing H&E or IHC stained tissue images, extracting tiles from gigapixel pathology…

★ 595GitHub stars
Hypothesis Generation✓SAFE B

jimmc414/Kosmos

Generate testable hypotheses. Formulate from observations, design experiments, explore competing explanations, develop predictions, propose mechanisms, for scientific inquiry across domains.

★ 595GitHub stars
Kegg Database✓SAFE B

jimmc414/Kosmos

Direct REST API access to KEGG (academic use only). Pathway analysis, gene-pathway mapping, metabolic pathways, drug interactions, ID conversion. For Python workflows with multiple databases, prefer bioservices. Use…

★ 595GitHub starsData & analysis
Latex Posters✓SAFE B

jimmc414/Kosmos

Create professional research posters in LaTeX using beamerposter, tikzposter, or baposter. Support for conference presentations, academic posters, and scientific communication. Includes layout design, color schemes,…

★ 595GitHub stars
Markitdown✓SAFE B

jimmc414/Kosmos

Convert various file formats (PDF, Office documents, images, audio, web content, structured data) to Markdown optimized for LLM processing. Use when converting documents to markdown, extracting text from PDFs/Office…

★ 595GitHub stars
Matchms✓SAFE B

jimmc414/Kosmos

Mass spectrometry analysis. Process mzML/MGF/MSP, spectral similarity (cosine, modified cosine), metadata harmonization, compound ID, for metabolomics and MS data processing.

★ 595GitHub stars
Molfeat✓SAFE B

jimmc414/Kosmos

Molecular featurization for ML (100+ featurizers). ECFP, MACCS, descriptors, pretrained models (ChemBERTa), convert SMILES to features, for QSAR and molecular ML.

★ 595GitHub stars
Networkx✓SAFE B

jimmc414/Kosmos

Comprehensive toolkit for creating, analyzing, and visualizing complex networks and graphs in Python. Use when working with network/graph data structures, analyzing relationships between entities, computing graph…

★ 595GitHub stars
Neurokit2✓SAFE B

jimmc414/Kosmos

Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal…

★ 595GitHub stars
Openalex Database✓SAFE B

jimmc414/Kosmos

Query and analyze scholarly literature using the OpenAlex database. This skill should be used when searching for academic papers, analyzing research trends, finding works by authors or institutions, tracking citations,…

★ 595GitHub starsData & analysis
Opentrons Integration✓SAFE B

jimmc414/Kosmos

Lab automation platform for Flex/OT-2 robots. Write Protocol API v2 protocols, liquid handling, hardware modules (heater-shaker, thermocycler), labware management, for automated pipetting workflows.

★ 595GitHub stars