Skills by risk · page 309

Highest-trust agent skills

7,952 skills rated SAFE with grade A or B, best score first. All are grade B today: grade A needs a sandboxed run we do not do for skills yet. Ties are broken by stars, so a repository with many skills can fill a page.

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ModelsAtlas. “Highest-trust agent skills”. Retrieved 29 Oct 2026. https://modelsatlas.com/skills/trusted/page/309
7,952 SAFE skills · page 309 of 332 · ranked by trust score, then stars

Clinvar Database

jimmc414/Kosmos

✓SAFE B

Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.

★ 59589/100

Cobrapy

jimmc414/Kosmos

✓SAFE B

Constraint-based metabolic modeling (COBRA). FBA, FVA, gene knockouts, flux sampling, SBML models, for systems biology and metabolic engineering analysis.

★ 59589/100

Datacommons Client

jimmc414/Kosmos

✓SAFE B

Work with Data Commons, a platform providing programmatic access to public statistical data from global sources. Use this skill when working with demographic data, economic indicators, health statistics, environmental…

★ 59589/100

Denario

jimmc414/Kosmos

✓SAFE B

Multiagent AI system for scientific research assistance that automates research workflows from data analysis to publication. This skill should be used when generating research ideas from datasets, developing research…

★ 59589/100

Docx

jimmc414/Kosmos

✓SAFE B

Document toolkit (.docx). Create/edit documents, tracked changes, comments, formatting preservation, text extraction, for professional document processing.

★ 59589/100

Ena Database

jimmc414/Kosmos

✓SAFE B

Access European Nucleotide Archive via API/FTP. Retrieve DNA/RNA sequences, raw reads (FASTQ), genome assemblies by accession, for genomics and bioinformatics pipelines. Supports multiple formats.

★ 59589/100

Esm

jimmc414/Kosmos

✓SAFE B

Comprehensive toolkit for protein language models including ESM3 (generative multimodal protein design across sequence, structure, and function) and ESM C (efficient protein embeddings and representations). Use this…

★ 59589/100

Exploratory Data Analysis

jimmc414/Kosmos

✓SAFE B

Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and…

★ 59589/100

Fda Database

jimmc414/Kosmos

✓SAFE B

Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.

★ 59589/100

Get Available Resources

jimmc414/Kosmos

✓SAFE B

This skill should be used at the start of any computationally intensive scientific task to detect and report available system resources (CPU cores, GPUs, memory, disk space). It creates a JSON file with resource…

★ 59589/100

Gtars

jimmc414/Kosmos

✓SAFE B

High-performance toolkit for genomic interval analysis in Rust with Python bindings. Use when working with genomic regions, BED files, coverage tracks, overlap detection, tokenization for ML models, or fragment analysis…

★ 59589/100

Histolab

jimmc414/Kosmos

✓SAFE B

Digital pathology image processing toolkit for whole slide images (WSI). Use this skill when working with histopathology slides, processing H&E or IHC stained tissue images, extracting tiles from gigapixel pathology…

★ 59589/100

Hypothesis Generation

jimmc414/Kosmos

✓SAFE B

Generate testable hypotheses. Formulate from observations, design experiments, explore competing explanations, develop predictions, propose mechanisms, for scientific inquiry across domains.

★ 59589/100

Kegg Database

jimmc414/Kosmos

✓SAFE B

Direct REST API access to KEGG (academic use only). Pathway analysis, gene-pathway mapping, metabolic pathways, drug interactions, ID conversion. For Python workflows with multiple databases, prefer bioservices. Use…

★ 59589/100

Latex Posters

jimmc414/Kosmos

✓SAFE B

Create professional research posters in LaTeX using beamerposter, tikzposter, or baposter. Support for conference presentations, academic posters, and scientific communication. Includes layout design, color schemes,…

★ 59589/100

Markitdown

jimmc414/Kosmos

✓SAFE B

Convert various file formats (PDF, Office documents, images, audio, web content, structured data) to Markdown optimized for LLM processing. Use when converting documents to markdown, extracting text from PDFs/Office…

★ 59589/100

Matchms

jimmc414/Kosmos

✓SAFE B

Mass spectrometry analysis. Process mzML/MGF/MSP, spectral similarity (cosine, modified cosine), metadata harmonization, compound ID, for metabolomics and MS data processing.

★ 59589/100

Molfeat

jimmc414/Kosmos

✓SAFE B

Molecular featurization for ML (100+ featurizers). ECFP, MACCS, descriptors, pretrained models (ChemBERTa), convert SMILES to features, for QSAR and molecular ML.

★ 59589/100

Networkx

jimmc414/Kosmos

✓SAFE B

Comprehensive toolkit for creating, analyzing, and visualizing complex networks and graphs in Python. Use when working with network/graph data structures, analyzing relationships between entities, computing graph…

★ 59589/100

Neurokit2

jimmc414/Kosmos

✓SAFE B

Comprehensive biosignal processing toolkit for analyzing physiological data including ECG, EEG, EDA, RSP, PPG, EMG, and EOG signals. Use this skill when processing cardiovascular signals, brain activity, electrodermal…

★ 59589/100

Openalex Database

jimmc414/Kosmos

✓SAFE B

Query and analyze scholarly literature using the OpenAlex database. This skill should be used when searching for academic papers, analyzing research trends, finding works by authors or institutions, tracking citations,…

★ 59589/100

Opentrons Integration

jimmc414/Kosmos

✓SAFE B

Lab automation platform for Flex/OT-2 robots. Write Protocol API v2 protocols, liquid handling, hardware modules (heater-shaker, thermocycler), labware management, for automated pipetting workflows.

★ 59589/100

Paper 2 Web

jimmc414/Kosmos

✓SAFE B

This skill should be used when converting academic papers into promotional and presentation formats including interactive websites (Paper2Web), presentation videos (Paper2Video), and conference posters (Paper2Poster).…

★ 59589/100

Pathml

jimmc414/Kosmos

✓SAFE B

Computational pathology toolkit for analyzing whole-slide images (WSI) and multiparametric imaging data. Use this skill when working with histopathology slides, H&E stained images, multiplex immunofluorescence (CODEX,…

★ 59589/100